Skin Care

Demodex Mites and Rosacea: Therapy Strategies and Causes


Demodex mites in rosacea – it is confirmed by scientific info [5] that Demodex mites play an necessary position in rosacea! Anybody with rosacea is aware of how irritating the situation is and the way few good remedy choices there are to maintain a remission. I’ve lengthy been treating my rosacea sufferers by combining medicines and skincare suggestions to assist heal rosacea inclined pores and skin and stop reoccurance by ‘masking all of the bases’ we all know play a task in rosacea – together with addressing mites.

Data is energy. This information lets you acquire management of rosacea and the infamous Demodex mites. We glance into remedy plans, one of the best routines and handiest merchandise, and the very nature of those pesky microscopic foes. You’ll be outfitted to efficiently conquer facial mites and facial redness, pores and skin sensitivity, rosacea bumps, and obtain a radiant, wholesome complexion.

Scientists Have Been Rethinking the Significance of Mites in Rosacea!

Researchers proceed to unravel the advanced relationship between Demodex mites and rosacea.

We have lengthy identified that:

  • Each individual has Demodex mites of their pores and skin pores (sure, it is unsavory however true).
  • Folks with rosacea have much more mites of their pores than regular.

As a result of everyone has Demodex mites, tiny creatures that reside naturally in our pores, docs have ignored their presence. I haven’t. Over a few years, I would see mite stuffed pores below the microscope as an incidental discovering on pores and skin biopsies. I would famous that it typically correlated with run-away rosacea [6] together with pustules, purple delicate pores and skin, and sometimes patches of pores and skin with small spikes of whitish scale protruding of facial pores that have been surrounded by redness (pityriasis folliculorum). Due to this, I’ve been treating Demodex mites for many years and located that my rosacea affected person’s pores and skin improves once I do!

I am thrilled that current scientific research are giving us some attention-grabbing info that helps my remedy strategies. 

Outcomes of increasingly more scientific papers are suggesting a major position for Demodex mites in driving rosacea of each facial pores and skin and the eyes. In reality, authors of a scientific overview paper [7] on rosacea and Demodex say this in regards to the position of Demodex in rosacea:

“Rosacea favors the proliferation of Demodex, and the over-proliferation of Demodex aggravates the signs of rosacea, thus forming a vicious circle.”

We glance deeper into the connection between mites and rosacea, together with causes, micro organism on mites, pores and skin issues, eyelash mites, mites on scalps, and different info under. However first let’s have a look at your Demodex mites and rosacea remedy choices:

What’s the Therapy for Demodex Mites and Rosacea

The care tips for rosacea are always evolving. Within the 35+ years that I’ve practiced dermatology, the usual rosacea therapies have relied on oral and topical antibiotics. We don’t know fully why antibiotics helped rosacea. It could be by concentrating on micro organism which can be current within the pores and skin or on the mites. Some antibiotics even have anti–inflammatory results separate from their antibacterial properties.

A lot of my sufferers are unwilling to make use of antibiotics long run so I’ve labored onerous to search out different remedies – together with addressing mites.

Dr. Bailey’s Pores and skin Care Technique

Science and A long time of Expertise Backed Substances and Technique

I developed my suggestions primarily based on what labored for my many rosacea sufferers and observations I made below the microscope on pores and skin biopsies. When I’ve a suspicion that mites are taking part in a task in a affected person’s rosacea signs, my technique consists of two key elements:

  1. I embrace particular topical anti-mite prescription medicines (extra on this below)
  2. As a result of mite re-infestation is the norm, I additionally advocate particular skincare steps and merchandise to discourage mites from coming again and thriving in abundance

The strategy works synergistically to get rid of and management Demodex mites, soothe irritation, and reveal a more healthy, calmer complexion.

4-Step Pores and skin Care Routine to Deal with Rosacea and Demodex Mites

Complete skin care routine for a radiant skin.

Take management of rosacea and pesky Demodex mites with my Complete Skin Care Routine™ which consists of 4 important steps: Cleanse, Right, Hydrate, Shield. As a dermatologist, I’ve seen its transformative energy firsthand. 

This routine tackles each rosacea and its mitey culprits, leaving you with a calmer, clearer complexion, free from redness, bumps, and breakouts. Your pores and skin will really feel soothed, with minimized pores and mirror a wholesome, radiant glow.

Bear in mind, consistency and professional steerage are key for optimum outcomes!

The core of this routine is my Rosacea Therapy Kit, and I’ve strategically added the Benzoyl Peroxide Cream and Omega Enriched Face Booster Oil to deal with Demodex mites with rosacea.

Rosacea skin care treatment products kit.Benzoyl peroxide fights mites and bacteria.do essential oils kill demodex

Let’s have a look at use and layer these merchandise with the 4-step routine:

1. Cleanse

Floor cleaning can wash off Demodex mites outdoors the pores, together with pores and skin yeast. Facial pores and skin cleaning twice every day is necessary for controlling Demodex mites. [12]

  • Cleanse pores and skin with a 2% pyrithione zinc fortified soap (Calming Zinc) twice a day.
    • This helps steadiness a pores and skin yeast germ referred to as Pityrosporum/Malassezia that additionally grows abundantly on rosacea-prone complexions.
  • Delicate complexions do finest alternating the two% Calming Zinc cleaning soap within the morning with pH balanced soapless Extremely Gentle Foaming Facial Cleanser at evening.
  • For non-allergic sufferers, I could select a prescription pores and skin cleanser with sulfa medication if mandatory.

All the time rinse pores and skin rather well after cleaning as a result of retained cleanser will irritate pores and skin and proceed to tug pores and skin lipids out of pores and skin layers.

2. Right

Efficiently treating facial mites and rosacea is not nearly cleaning away mites, micro organism, yeast and impurities similar to useless pores and skin cells and extra sebum. Science has unlocked a treasure trove of focused corrective substances and potent remedies, ready to be mixed and layered into a customized routine that unleashes their true potential.

  • To right out of steadiness pores and skin irritation, I at all times have my sufferers apply Green Tea Antioxidant Skin Therapy first, proper after the cleaning and towel drying the pores and skin.
    • This soothing cream incorporates pharmaceutically pure and secure inexperienced tea polyphenols equal to what’s extracted in 500 cups of inexperienced tea.
    • This well-liked topical product masses the pores and skin’s antioxidant reserve to assist battle pores and skin stressors.
  • For greasy pustular rosacea and irritation, attempt making use of Benzoyl Peroxide Cream twice a day to energetic areas. It may be irritating however can typically even be very uniquely acceptable and may probably handle mites.
  • If topical medicines are getting used, similar to metronidazolel, Finacea or ivermectin/Soolantra (which particularly kills Demodex mites), I’ve my sufferers layer these on prime of the Inexperienced Tea cream.

Professional-tip: I prescribe the very economical permethrin cream to my rosacea sufferers and have them apply it to their face and neck twice a day for every week after which twice a day for 1 to 2 days each month to manage Demodex mites. It is a distinctive remedy that I developed so ask your dermatologist if this is likely to be best for you.

3. Hydrate

The hydrate step is necessary as a result of barrier integrity is weak in rosacea-prone pores and skin. Your pores and skin will not heal if it isn’t correctly hydrated.

  • Hydrate your pores and skin with Daily Moisturizing Face Cream utilized over the merchandise you used above.
  • Enrich the Day by day Moisturizing Face Cream with a couple of drops of the Omega Enriched Face Booster Oil to learn from the important oils (similar to sea buckthorn) and castor seed oil.
  • At evening, it’s possible you’ll even need to change the Moisturizing Cream with the Omega Oil. on to your face.

4. Shield

The defend step is absolutely necessary for controlling rosacea as a result of UV publicity can set off rosacea flares. My best choice for every day solar safety for rosacea inclined complexions is a mineral zinc oxide broad spectrum sunscreen.

  • Apply the non-irritating Sheer Strength Physical Matte Tinted SPF 50+ Sunscreen through the day – each day – to stop UV triggering of rosacea.
    • It’s calmly tinted with iron oxide to assist conceal complexion flaws. It blends in effectively to all complexion pores and skin tones, together with actually honest pores and skin.
    • Males like it too as a result of it does NOT appear to be make-up.
    • The matte texture helps conceal oily shine.
    • The iron oxide helps filter seen and blue display screen mild identified to trigger pores and skin harm.

It is that straightforward! This non-prescription dermatologist’s Full Pores and skin Care Routine covers all the predominant elements that trigger rosacea, set off rosacea, or are the results of rosacea, full with focused merchandise that management Demodex mites. If mandatory, I mix these focused skincare merchandise with topical prescription medicines to deal with rosacea.

Comply with the 4-Step Routine with the Rosacea Remedy Equipment

I created my Rosacea Therapy Kit to take the guesswork out of constructing a therapeutic skincare routine for these affected by rosacea. The above steps add within the  Benzoyl Peroxide Cream and Omega Enriched Face Booster Oil to successfully battle demodex mites with rosacea.

Rosacea skin care treatment products kit.Benzoyl peroxide fights mites and bacteria.do essential oils kill demodex

If you have already got a pH balanced cleanser (utilized in step 1) and an SPF (utilized in step 4) that you just love, my Facial Flaking and Redness Solution Kit mix the important thing non-prescription merchandise I take advantage of to focus on driving elements behind rosacea irritation.

How the Routine Works

This fastidiously curated number of suitable merchandise works collectively to heal rosacea, increase your pores and skin’s resilience in opposition to irritation and mite overgrowth, and finally assist sustained remission. For a temperamental situation like rosacea, this complete strategy delivers the absolute best outcomes.

This routine:

  • Fights irritation with antioxidants from inexperienced tea
  • Contains substances that will battle mites and micro organism similar to benzoyl peroxide, castor seed oil and sea buckthorn
  • Incorporates zinc pyrithione to battle pores and skin yeast that we’ve lengthy identified contribute to facial redness from rosacea
  • Helps the delicate pores and skin barrier to heal with a lipid replenishing facial moisturizer
  • Prevents UV ray publicity that may set off rosacea utilizing a non-irritating zinc oxide sunscreen
Proper skin care can help treat rosacea and Demodex mites.
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Medical Remedies Utilized by Dermatologists to Deal with Demodex Mites in Rosacea

How I’ve Been Treating Facial Demodex Mites in Rosacea Sufferers

Right here, I record a number of the Demodex mites remedy choices I’m going over with my rosacea sufferers. It is very important talk about these together with your treating doctor to see if they’re best for you.

do demodex mites cause rosacea Demodex folliculorum in the human pore

My Rosacea Therapy Kit is the core of a skincare routine that helps prescription care in order that your rosacea heals. To deal with Demodex mites, my 4-step skincare routine provides in Benzoyl Peroxide Cream and Omega Enriched Face Booster Oil. (After all, talk about your skincare routine together with your prescribing physician in case you are receiving prescription medicines.)

What Kills Demodex Mites?

Does Benzoyl Peroxide Kill Demodex Mites?

Years in the past, I attended an American Academy of Dermatology lecture given by a doctor practising in Israel the place they use benzoyl peroxide for Demodex. Permethrin was not out there there and topical ivermectin had but to be invented. This doctor stated she achieved good management of facial Demodex infestation and rosacea pustules with topical benzoyl peroxide.

Benzoyl peroxide is used within the veterinary medical literature to assist management Demodex pores and skin infestations in canines. As well as, the benzoyl peroxide-erythromycin topical drugs mixture has been discovered useful for treating facial demodex infestation in people. [13]

Benzoyl peroxide could be irritating to delicate rosacea-prone pores and skin nonetheless. I take advantage of my alcohol-free Benzoyl Peroxide Cream for complexions affected by rosacea. Comply with the 4-step skincare routine on this information to include it into your routine.

Another choice is Foaming Benzoyl Peroxide Cleanser. This mild pH balanced cleanser has a full 10% benzoyl peroxide. Delicate pores and skin rosacea-prone complexions might not tolerate benzoyl peroxide so care should be taken.

Do Antibiotics Kill Demodex?

No, antibiotics usually are not antiparasitic medicines. However topical and oral antibiotics have been the mainstay of rosacea remedy for years. They could assist cut back mite numbers, sluggish the return of mites, goal the micro organism on the mites that play a task in rosacea and will exert anti-inflammatory results on rosacea infected pores and skin.

Is there a Pure Therapy for Demodex Mites?

Some important oils seem to kill Demodex mites however on the concentrations used, these oils could be irritating to rosacea. Tea tree, sage, and peppermint have been the best in a small research [3], although all oils finally killed Demodex together with sea buckthorn, which is a soothing oil that helps calm pores and skin irritation.

My Omega Enriched Face Booster Oil (utilized in step 3 of my skincare routine) incorporates sea buckthorn and castor seed oil, each of which have been studied in opposition to Demodex, with different botanical therapeutic oils similar to borage, kakui nut, argan oil, pomegranate oil, cypress and others to sooth and assist delicate pores and skin.

I feel there’s a position for every day botanical oil use to assist management the Demodex mite recolonization of rosacea-prone pores and skin. I personally apply my Omega Oil at bedtime on prime of my different nighttime remedy merchandise. My 4-step skincare routine guides you on use this oil in your rosacea remedy.

Does Pyrithione Zinc Kill Demodex Mites?

Zinc pyrithione in my Calming Zinc Soap (utilized in step 1 of the routine) has been useful for controlling rosacea. Whether or not it helps decelerate mites, or their micro organism, or is simply engaged on Pityrosporum/Malassezia yeast, it’s not absolutely understood, however it’s efficient and I at all times advocate it. A Russian research achieved in 2012 confirmed that pyrithione zinc decreased each Malassezia pores and skin yeast and demodex mites in sufferers with seborrheic dermatitis. Seborrhea and rosacea typically overlap, as does this yeast and the mites.

Comply with the skin care routine above, which includes this Zinc Cleaning soap with different complimentary merchandise to assist battle rosacea and Demodex mites.

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The Relationship Between Facial Mites and Rosacea

Do Demodex Mites within the Pores Trigger Rosacea?

The pores in your pores and skin are dwelling to many microscopic inhabitants together with micro organism, yeast, and – sure – mites. The rosacea puzzle is taking kind and microscopic Demodex mites play an necessary position within the pores and skin issues of rosacea! [1] Mammals, together with people, have Demodex on their pores and skin. Demodex mites primarily reside in our pores and oil glands.

Demodex mites:

  • Desire the oiliest components of our face such because the “T-zone”.
  • Eat useless pores and skin cells and sebum (pores and skin oil).
  • Are shy! The mites hardly ever enterprise out of the pores the place they reside, lay their eggs, and die.

Precisely how mites trigger rosacea is advanced and nonetheless being labored out. We all know that Demodex mites can weaken pores and skin barrier integrity. This results in extreme pores and skin sensitivity to traditional rosacea triggers similar to harsh climate, skincare merchandise and even solar.

A few of the early indicators of rosacea, together with flushing, redness and ‘damaged capillaries’ [5], additionally happen when there are elevated numbers of mites within the pores. The purple pores and skin bumps of rosacea, referred to as granulomas, occur when pores and skin immune cells acquire round mite stuffed pores.

Research additionally counsel that the overgrowth of Demodex mites might finally alter the pores and skin’s immune steadiness and capillary perform in ways in which favor the mite’s personal survival and proliferation. [5] As if the mite-skin interplay isn’t difficult sufficient, further papers  means that it’s not simply the mites, it’s a protein on a micro organism [8] that the mites carry that causes a number of the irritation of rosacea – wow, you may see how this subject is difficult – and the mite/micro organism/rosacea connection could also be one of many the explanation why antibiotics have been one of many useful medicines used to deal with rosacea for a few years!

What Rosacea Pores and skin Issues are Linked to Demodex Mites?

  1. Pores and skin barrier fragility (delicate pores and skin)
  2. Flushing
  3. Everlasting “damaged” facial capillaries
  4. Sebaceous hyperplasia (enlargement of oil glands)
  5. The purple rash, bumps and pustules of rosacea

Folks with Rosacea Have Extra Mites in Their Pores

Whereas we have identified that rosacea inclined complexions have a larger variety of mites within the pores, the precise relationship remained a thriller for years. The connection between Demodex mites and rosacea is turning into more and more clear. Demodex mites are able to set off an inflammatory cascade that results in the signs of rosacea. Scientific research in medical journals have additionally gathered proof on how micro organism residing on human Demodex mites might play a vital position in triggering a posh cascade of occasions that result in the pores and skin issues of rosacea flares.

Many scientific papers now hyperlink the pores and skin issues attribute of rosacea similar to redness, bumps, extreme pores and skin sensitivity, flushing and elevated seen pores and skin capillaries with Demodex mites. This information paves the way in which for doubtlessly more practical and customized remedy choices sooner or later.

Please see my proven 4-step system on this information that mixes my Rosacea Therapy Kit with the mite-fighting duo of Benzoyl Peroxide Cream and Omega Enriched Face Booster Oil to actively goal and get rid of Demodex mites and rosacea.

Micro organism on Demodex Mites Could Be the Reason behind Rosacea Pores and skin Issues

There are two micro organism which may be guilty, Bacillus oleronius and Staphylococcus epidermidis. Curiously, these microbes are delicate to the antibiotics that we dermatologists have used for years to deal with rosacea. It could have been the mite’s micro organism that we have been treating all alongside. Conclusions have not been reached however it’s fascinating, stunning, and just a bit creepy. I talk about my strategy to medical remedies in the above section.

Eyelash Mites: Folks with Rosacea Have Extra Demodex Mites in Their Eyelash Follicles

Having rosacea means that you’re extra more likely to have an elevated variety of mites [9] within the hair follicles of your eyelashes. Demodex mites in eyelash hair follicles can lead to blepharitis with redness, swelling and itching of the pores and skin alongside the lash line. Dandruff [10] of the lashline with buildup of scale and crusting has additionally been linked to the presence of Demodex. It’s doable to have these eyelash signs with or with out occular rosacea.

See the Medical Treatments I use to deal with Demodex mites in eyelashes.

Demodex Mites Can Trigger Pustules, Redness, and Scale on the Scalp

Demodex within the hair follicles of the scalp could be related to a number of the similar signs of rosacea, particularly redness and pustules. [11] That stated, this doesn’t imply that having rosacea in your face means that you’ve got rosacea in your scalp. It does imply that you probably have numerous mites within the pores of your face and lash line, you might also have mites within the follicles of the scalp. The excellent news is that a number of the oral mite remedies (see my remedy strategy above) that assist management the mites driving your rosacea may handle mites alongside the lashline and within the hair follicles of your scalp.

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The Information About Demodex Mites on Our Pores and skin and Eyelashes

Demodex mites reside within the pores on locations of the human physique the place there may be numerous oil (T-zone, chest, ear canal, and groin). Solely hardly ever can they get via the liner of the pore and into the second layer of the pores and skin referred to as the dermis. Once they do, they could trigger extreme irritation similar to giant inflammatory pustules (pimples). It could be this entrance into the pores and skin that’s answerable for a number of the worst inflammatory elements of rosacea.

  • Demodex mites reside for lower than 3 weeks and their eggs hatch in lower than 3 days.
  • They need to be in a pore to outlive; they’ll’t reside outdoors the pore. They solely come out of the pore at evening to mate, touring at most ½ inch away from their dwelling for courting functions! When achieved, they scramble again down into their pore to put their eggs.
  • Human infants are born with no mites, after which their pores slowly develop into inhabited by them. Each race in all components of the world has Demodex mites – sorry to interrupt the information however none of us are spared!
  • As we age, we develop into extra more likely to have numerous mites in our pores. In reality, 100% of the aged have Demodex mites of their pores. It could be the standard of sebum (oil) not the amount that makes the pores hospitable for the mites for the reason that aged outpace teenagers in pores and skin mite density. There may be some aspect of immune underperformance on the a part of our pores and skin that enables the mites to thrive.
  • There are two forms of mites; they reside in numerous components of the pores and trigger completely different manifestations of rosacea.
    • Demodex folliculorum lives in the primary portion of the pore and it is extra more likely to trigger scaling redness and delicate pores and skin.
    • Demodex brevis lives deeper within the sebaceous glands (which comes off the pore) and is extra more likely to trigger the papulopustular eruption (rosacea pimples), the symmetrical rashes, and different pores and skin issues arising on the background of a pre-existing rosacea.
  • The B. oleronius micro organism are discovered on the Demodex mites that colonize human pores and skin. It could truly be a protein on the B. oleronius bacterium that’s able to resulting in a number of the necessary inflammatory cascade seen in rosacea together with ocular rosacea.
  • Demodex can act as a vector for micro organism and the mites presence is related to co-infecting pores and skin micro organism and fungi. This co-infection might play a task in pores and skin issues similar to chalazions, styes, pustules and purple bumps amongst others.

The Backside Line with Mites and Rosacea

The underside line is that we could also be getting nearer to understanding Demodex mites and rosacea. I anticipate to see extra focused remedies being developed, and possibly even a treatment, because the analysis continues. For now, the brand new give attention to mites is gross, however fascinating. As a ultimate be aware the authors of a research [1] state:

The pathogenic position of Demodex mites, in addition to B. oleronius and S. epidermidis, within the induction and persistence of rosacea stays an unresolved situation.

So, till then, we sufferers and physicians need to be inventive at attempting to reign within the irritation and pores and skin issues of rosacea.

Take Management of Rosacea and Demodex Mites

As a dermatologist, I’ve seen the frustration of persistent rosacea and Demodex flare-ups. The 4-step skin care routine outlined on this information combines the facility of the hand-selected merchandise in my Rosacea Remedy Equipment with the scientifically-backed advantages of Omega Enriched Face Oil and Benzoyl Peroxide Cream.

This constant strategy with a focused assault on each rosacea and Demodex mites helped me heal lots of my endurance with lasting outcomes.

By constructing your routine with these potent allies, layering them for max impression, you’ll unlock the door to a radiant, even-toned complexion. Your pores and skin can  be free from redness, irritation, and pesky bumps and resilient in opposition to on a regular basis stressors, each environmental and microscopic.

Discover Additional

If you need a extra in-depth dialogue on rosacea skincare, try the next guides:

Obtain a Free Copy of My Rosacea eBook

Study all about what it’s and what you are able to do about it.

Different articles you may study extra from:

 You may also go to my Skin Care Advice page and scroll all the way down to the Glossary the place you can see an inventory of my hottest rosacea articles.

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In regards to the Creator

Dr. Cynthia Bailey M.D. is a Board Licensed dermatologist practising dermatology since 1987. She has achieved effectively over 200,000 pores and skin exams throughout her profession and authors the longest working doctor written pores and skin well being weblog on the planet.

References

  1. The potential position of Demodex folliculorum mites and micro organism within the induction of rosacea.  Stanisław Jarmuda, Niamh O’Reilly, Ryszard Żaba, Oliwia Jakubowicz, Andrzej Szkaradkiewicz and Kevin Kavanagh Journal of Medical Microbiology Papers in Press . Printed August 29, 2012
  2. Therapy of demodicosis in canines: 2011 medical follow tips. Ralf S Mueller, Emmanuel Bensignor, Lluís Ferrer, Birgit Holm, Stephen Lemarie, Manon Paradis, Michael A Shipstone. National Center for Biotechnology Information, February 13, 2012 
  3. Impact of important oils on the survival fee of Demodex spp. Maciej Okay Oseka; Aleksandra Sedzikowska, iOVS Avro Journal, April 2014
  4. Dispelling the Thriller of Demodex, The Dermatologist, January 2007
  5. Forton FMN. The Pathogenic Function of Demodex Mites in Rosacea: A Potential Therapeutic Goal Already in Erythematotelangiectatic Rosacea? Dermatol Ther (Heidelb). 2020 Dec;10(6):1229-1253. doi: 10.1007/s13555-020-00458-9. Epub 2020 Oct 23. PMID: 33095403; PMCID: PMC7649190.
  6. Forton F, Germaux MA, Brasseur T, De Liever A, Laporte M, Mathys C, Sass U, Stene JJ, Thibaut S, Tytgat M, Seys B. Demodicosis and rosacea: epidemiology and significance in every day dermatologic follow. J Am Acad Dermatol. 2005 Jan;52(1):74-87. doi: 10.1016/j.jaad.2004.05.034. PMID: 15627084, PubMed
  7. Fen Wei, Li Li, Yi Kong, Xiaofeng Yan, Kevin J. Varghese, Music Zhang, Jian Jiang, Bao Chai, Hongxiang Chen; Proof for the Scientific Affiliation between Demodex and Rosacea: A Evaluate. Dermatology 2023; Karger
  8. Two AM, Wu W, Gallo RL, Hata TR. Rosacea: half I. Introduction, categorization, histology, pathogenesis, and threat elements. J Am Acad Dermatol. 2015 Could;72(5):749-58; quiz 759-60. doi: 10.1016/j.jaad.2014.08.028. PMID: 25890455, PubMed
  9. Gonzalez-Hinojosa D, Jaime-Villalonga A, Aguilar-Montes G, Lammoglia-Ordiales L. Demodex and rosacea: Is there a relationship? Indian J Ophthalmol. 2018 Jan;66(1):36-38. doi: 10.4103/ijo.IJO_514_17. PMID: 29283119; PMCID: PMC5778578 PubMed
  10. Cheng, A.M., Galor, A., Banoub, R. et al. The impression of ocular demodicosis on the eyes. Eye 37, 3061–3062 (2023).
  11. Helou W, Avitan-Hersh E, Bergman R. Demodex Folliculitis of the Scalp: Clinicopathological Research of an Unusual Entity. Am J Dermatopathol. 2016 Sep;38(9):658-63. doi: 10.1097/DAD.0000000000000512. PMID: 26959693. PubMed 
  12. Chudzicka-Strugała I, Gołębiewska I, Brudecki G, Elamin W, Zwoździak B. Demodicosis in Totally different Age Teams and Different Therapy Choices-A Evaluate. J Clin Med. 2023 Feb 19;12(4):1649. doi: 10.3390/jcm12041649. PMID: 36836184; PMCID: PMC9961532. MDPI
  13. Oztürkcan S, Ermertcan AT, Sahin MT, Afşar FS. Effectivity of benzoyl peroxide-erythromycin gel compared with metronidazole gel within the remedy of pimples rosacea. J Dermatol. 2004 Aug;31(8):610-7. doi: 10.1111/j.1346-8138.2004.tb00566.x. PMID: 15492433; PubMed 

Extra Research Referenced

Zhao YE, Wu LP et. al., Retrospective evaluation of the affiliation between Demodex infestation and rosacea,  Arch Dermatol. 2010 Aug;146(8):896-902

Elston DM, Demodex mites: info and controversies, Clin Dermatol. 2010 Sept-Oct;28(5):502-4

Li J, O’Reilly N, et. al., Correlation between ocular Demodex infestation and serum immunoreactivity to Bacillus proteins in sufferers with facial rosacea, Ophthalmology. 2010 Could;117(5):870-877

Gao YY, Di Pascuale MA, In vitro and in vivo killing of ocular Demodex by tea tree oil, Br J Ophthalmol 2005 Nov;89(11);1468-73

Forton FM. Papulopustular rosacea, pores and skin immunity and Demodex: pityriasis folliculorum as a lacking hyperlink. J Eur Acad Dermatol Venereol. 2012 Jan;26(1):19-28. doi: 10.1111/j.1468-3083.2011.04310.x. Epub 2011 Oct 24. PMID: 22017468.

Kim JS, Website positioning BH, Cha DR, Suh HS, Choi YS. Upkeep of Remission after Oral Metronidazole Add-on Remedy in Rosacea Therapy: A Retrospective, Comparative Research. Ann Dermatol. 2022 Dec;34(6):451-460. doi: 10.5021/advert.22.093. PMID: 36478427; PMCID: PMC9763916.

MOKRONOSOVA M.A., GLUSHAKOVA A.M., GOLYSHEVA E.V., ZHELTIKOVA T.M. Demodex mites and Malassezia yeast at sufferers with seborrheic dermatitis // Vestnik dermatologii i venerologii. – 2012. – Vol. 88. – N. 3. – P. 92-98. doi: 10.25208/vdv693



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